The staircase phenomenon in ventricular muscle
نویسندگان
چکیده
منابع مشابه
The staircase phenomenon at the corrugator supercilii muscle in comparison with the hand muscles.
BACKGROUND Phonomyography (PMG) is a novel method to monitor neuromuscular block. It is non-invasive and can be applied to any muscle. It can be used interchangeably with mechanomyography (MMG). The staircase phenomenon has not been investigated for this method or at the corrugator supercilii muscle. The purpose of this work was to determine the staircase effect at three different muscles using...
متن کاملThe staircase phenomenon: implications for monitoring of neuromuscular transmission.
BACKGROUND Repeated indirect stimulation enhances the evoked mechanical response of muscle (the staircase phenomenon). There are few data that document the magnitude of this effect in man. Inexpensive acceleromyographic monitors of neuromuscular function are now available. If these units are to be used as scientific tools or clinical monitors, additional information regarding how to achieve pro...
متن کاملStaircase in frog ventricular muscle. Its dependence on membrane excitation and extracellular ionic composition.
Staircase was studied in frog ventricle strip preparations where it was possible to alter extracellular ionic composition extremely rapidly in the diastolic interval between beats. Several findings strongly indicate that staircase in this tissue is a result of progressively increasing calcium influx per beat, rather than a beat-by-beat augmentation of an intracellular calcium pool which contrib...
متن کاملA Study of the "Staircase" in Ventricular Muscle and Its Relationship to the Inotropic Activity of Certain Drugs
Tension duration curves recorded during isometric contractions of toad ventricular strips were studied under a variety of conditions. Changes recorded in these curves during inotropic responses could be divided into two classes: (a) those in which the time required to reach peak tension (t(p)) was decreased and the twitch duration shortened. (b) those in which t(p) was either unaltered or incre...
متن کاملStaircase in mammalian muscle without light chain phosphorylation.
In disuse atrophied skeletal muscle, the staircase response is virtually absent and light chain phosphorylation does not occur. The purpose of the present study was to determine if staircase could be restored in atrophied muscle with continued absence of myosin light chain phosphorylation, by reducing what appears to be an otherwise enhanced calcium release. Control (untreated) and sham-operate...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1932
ISSN: 0022-3751
DOI: 10.1113/jphysiol.1932.sp002868